Surgical Oncology Research
Our faculty and residents engage in clinical research. Sample publications are listed below.
Aguirre, Salvador; Haley, Jill K; Broski, Julie A; Baker, Jordan; Selby, Luke V; Umar, Shahid; Al-Kasspooles, Mazin F. (2025) Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Cytoreductive Surgery (CRS): Age-Related Outcomes and a Look Into the Future. Cancers, 17(3), 486. 10.3390/Cancers17030486
Arnold, Levi; Yap, Marrion; Farrokhian, Nathan; Jackson, Laura; Barry, Michael; Ly, Thuc; Arjunan, Pachiappan; Kaczorowski-Worthley, Angela; Tews, Carter; Pandey, Avisha; Morrison, Austin; Washburn, Michael P; Standing, David; Gomez, Juan P; Yellapu, Nanda Kumar; Johnson, David; Li, Linheng; Umar, Shahid; Anant, Shrikant; Thomas, Sufi Mary. (2025) Dclk1-Mediated Regulation of Invadopodia Dynamics and Matrix Metalloproteinase Trafficking Drives Invasive Progression in Head and Neck Squamous Cell Carcinoma. Molecular Cancer, 24(1), 50. 10.1186/S12943-025-02264-3
Del Zompo, Fabio; Crouchet, Emilie; Ostyn, Tessa; Dhawan, Punita; Baumert, Thomas F. (2025) Claudin-1 Is a Mediator and Therapeutic Target in Primary Sclerosing Cholangitis. Journal of Hepatology, 83(6), 1305-1319. 10.1016/J.jhep.2025.08.005
Gowrikumar, Saiprasad; Tarudji, Aria; Mcdonald, Brandon Z; Balusa, Sai Sindhura; Kievit, Forrest M; Dhawan, Punita. (2025) Claudin-1 Impairs Blood–Brain Barrier by Downregulating Endothelial Junctional Proteins in Traumatic Brain Injury. Tissue Barriers, 13(4), 2470482. 10.1080/21688370.2025.2470482
Liu, Shanglei; Cox, Kristin E; Dhawan, Punita; Bouvet, Michael. (2025) Enhanced Visualization of Colonic Polyps Using a Fluorophore-Conjugated Claudin-1 Antibody in a CPC-APC Mouse Model. Journal of Gastrointestinal Surgery, 102103. 10.1016/J.gassur.2025.102103
Primeaux, Mark; Gupta, Ritika; Fatima, Iram; Talib, Sumbal; Singh, Amar B; Mohs, Aaron M; Bouvet, Michael; Dhawan, Punita. (2025) A Claudin-1 Near-Infrared Fluorescent Antibody Conjugate for in Vivo Primary and Metastatic Colorectal Cancer Detection. Molecular Imaging and Biology. 10.1007/S11307-025-02060-X
Skupa, Sydney; Cooper, Kathryn M; Dhawan, Punita; Talmon, Geoffrey A; D’angelo, Christopher R; El-Gamal, Dalia. (2025) Gut Microbiome Profiling in Eμ-Tcl1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia. Cancer Research Communications, 5(8), 1344-1358. 10.1158/2767-9764.Crc-25-0022
Yusuf, Kafayat; Roy, Badal C; Hauser, William L; Al-Kasspooles, Mazin; Sanchez, Sierra; Attard, Thomas M; Pei, Dong; Sampath, Venkatesh; Anant, Shrikant; Umar, Shahid. (2025) Dclk1 Isoform (Dclk1-S) as a Critical Player in Promoting Inflammation, Tissue Remodeling, and EMT in Mouse Models of Colitis. PLOS Pathogens, 21(8), E1013360. 10.1371/Journal.ppat.1013360
Standing, D; Ashcraft, John; Umar, Shahid; Et al. (2023) Doublecortin-Like Kinase 1 Is a Therapeutic Target in Squamous Cell Carcinoma. Molecular Carcinogenesis, 62(2), 145-159. 10.1002/Mc.23472
Stewart, Jeremy; Fleishman, Nathan R; Staggs, Vincent S; Thomson, Mike; Stoecklein, Nicole; Lawson, Caitlin E; Washburn, Michael P; Umar, Shahid; Attard, Thomas M. (2023) Small Intestinal Polyp Burden in Pediatric Peutz-Jeghers Syndrome Assessed Through Capsule Endoscopy: a Longitudinal Study. Children, 10(10), 1680. 10.3390/Children10101680