Nizar Talaat, MD

Professional Background

I am a quadruple board-certified physician in Internal Medicine, Gastroenterology, Transplant Hepatology, and Clinical Informatics. I serve as an Associate Professor of Medicine at the University of Kansas Health System and Program Director of the Transplant Hepatology Fellowship, where I lead clinical and educational initiatives in advanced liver disease and transplantation.

As a physician informaticist, I serve as the Solid Organ Transplant Informatics Lead and Gastroenterology and Hepatology Informatics Officer, directing efforts to optimize clinical workflows, enhance EHR functionality, and improve data integrity across transplant and hepatology programs. My work focuses on leveraging informatics to streamline transplant pathways, improve care coordination, and support high-quality, patient-centered care.

My clinical and research interests center on advanced liver disease and liver transplantation, with a focus on clinical informatics, population health, and real-world data. I am particularly interested in developing decision support tools, improving adherence to cirrhosis quality measures, and advancing predictive modeling in hepatology.

I am actively involved in national initiatives, serving as chair on the Epic Hepatology Steering Board and as a founding member of the American Association for the Study of Liver Diseases (AASLD) Clinical Informatics and Digital Health Special Interest Group. I’m also a member of the AASLD Communication and Technology Committee.

I currently serve as a principal-investigator on multicenter clinical trials evaluating novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) and cancer immunotherapy in autoimmune liver disease. I am also involved in large-scale observational studies examining real-world trends in chronic liver disease management, healthcare disparities, and the impact of digital health interventions on cirrhosis care.

Through ongoing collaborations in transplant informatics and hepatology research, I aim to drive data-informed interventions that are clinically impactful, scalable, and equitable.

• MBBS, Bachelor of Medicine, Bachelor of Surgery, University of Khartoum, Khartoum, Sudan
• Residency, Internal Medicine, Oakwood Hospital and Medical Center. Dearborn, MI, Dearborn, Michigan
• Post Doctoral Fellowship, Hepatology, University of Michigan. Ann Arbor, Michigan, Ann Arbor, Michigan
• Clinical Fellowship, Hepatology, University of Missouri. Columbia, Missouri., Columbi, Missouri
• Clinical Fellowship, Gastroenterology, East Carolina University. Greenville, North Carolina, Greenville, North Carolina
• Clinical Fellowship, Transplant Hepatology, Mayo Clinic. Rochester, Minnesota, Rochester, Minnesota

• Society of Liver Disease in Africa (SOLDA), Member, 2023 - Present
• European Association for study of liver disease (EASL), Member, 2021 - Present
• American Association for the Study of Liver disease (AASLD), Member, 2012 - Present
• Sudanese American Medical Assosciation (SAMA), Member, 2011 - Present

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Research

Overview

My research focuses on improving care delivery and outcomes in liver disease and solid organ transplantation through clinical informatics, population health, and real-world data. I leverage electronic health record data and decision support tools to optimize transplant evaluation pathways, enhance adherence to cirrhosis quality measures, and develop predictive models in hepatology.
I serve as a principal investigator on multicenter clinical trials evaluating novel therapies for metabolic dysfunction-associated steatohepatitis (MASH) and cancer immunotherapy in autoimmune liver disease. My work also includes large observational studies examining care patterns, disparities in access and screening, and the impact of digital health interventions on cirrhosis management.
My prior research has addressed disparities in hepatocellular carcinoma and colorectal cancer screening, as well as EHR-driven quality improvement in cirrhosis. I aim to develop scalable, data-driven interventions that advance equitable and high-value care in hepatology and transplantation.