Iram Fatima, Ph.D.

Professional Background

Dr. Iram Fatima, Ph.D. is a Research Instructor in the Department of Surgery at the University of Kansas Medical Center (KUMC). With a strong background in cancer biology, therapeutics, and chemoprevention, her research focuses on understanding the molecular mechanisms of gastrointestinal cancers. She earned her PhD in 2014 from the Central Drug Research Institute (CDRI), India and has held research positions at the University of Nebraska Medical Center (UNMC) and the University of Tennessee Health Science Center (UTHSC), USA.

Research

Overview

Dr. Fatima’s research focuses on unraveling the molecular mechanisms underlying gastrointestinal cancers, with a particular emphasis on epithelial barrier physiology and cell cycle regulation. Her work explores the roles of tight junction protein Claudin-1 and cell cycle protein MASTL in cancer progression and their potential as therapeutic targets. She is actively involved in the development of novel therapeutic inhibitors, organoid and tumoroid models, genetically modified cell lines, and genetically engineered mouse models to advance cancer therapy and prevention.