Halinder S. Mangat, M.D., M.Sc.

Professional Background

Halinder Mangat, M.D., is an associate professor in the Department of Neurology and a neurocritical care specialist with The University of Kansas Health System. He joined KU Medical Center in 2021 after eight years on the faculty at Weill Cornell Medical College in New York. He is an adjunct Assistant professor at Weill Cornell Medical College, Adjunct Associate Professor at Uniformed Services University of Health Sciences, Bethesda, and is Director of Research for the Brain trauma Foundation. Dr. Mangat also serves as a permanent council member of the G4 Alliance.

Dual certified in internal medicine and neurology, Dr. Mangat spent two years as a research fellow in neurochemistry at the Karolinska Institute in Stockholm, Sweden, and subsequently completed his fellowship in neurocritical care at Addenbrooke's Hospital/Cambridge University Hospitals, UK. He also earned a master's degree in public health for global practice from the London School of Hygiene and Tropical Medicine.

Dr. Mangat's interests are in global neurotrauma, especially in low-middle income countries. He has worked for nearly a decade in a capacity building program in Tanzania. Additionally, he dedicates research time in advanced clinical neurovascular physiology monitoring techniques using invasive devices such as cerebral microdialysis and cerebral oximetry to understand early brain injury in the acutely injured brain.
He is currently the PI on a Department of Defense funded multi center phase 1 clinical trial on safety of lumbar drainage in severe TBI, and is also funded as a subject matter and methodology liaison at the Military TBI Initiative - Brain Trauma Foundation center of excellence for Guidelines on TBI.
In addition, Dr. Mangat is part of the Global Coalition for TBI which is working ​towards tabling a resolution at the annual ​World Health Assembly meeting in 2026 to ​recognize TBI as a chronic and notifiable condition.

• MBBS, Medicine, St. John's Medical College, Bangalore, India
• MPH, Public Health for Developing Countries, London School of Hygiene & Tropical Medicine, London, United Kingdom
• Other, Respiratory Medicine, St. Johns Medical College, Bangalore, India
• Other, Neurochemistry, Karolinska Institute, Stockholm, Sweden
• Residency, Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR
• Residency, Neurology, New York University Hospital, New York, NY
• Other, Neurochemistry, Karolinska Institute, Stockholm, Sweden
• Clinical Fellowship, Neurocritical Care, University of Cambridge, Cambridge, United Kingdom
• Residency, Neurology, Mt. Sinai School of Medicine, New York, NY

• Internal Medicine Board Certification, American Board of Internal Medicine
• Kansas License, Kansas Board of Healing Arts
• Neurocritical Care, American Board of Psychiatry and Neurology
• Neurology Board Certification , American Board of Psychiatry and Neurology

• Neurocritical Care Society, Guidelines committee, Member, 2024 - 2027
• Neurocritical Care Society, Mentor-Mentee Program, Faculty Mentor, 2020 - Present
• Neurocritical Care Society, Annual Meeting Committee, Member, 2018 - 2021
• Neurocritical Care Society, Traumatic Brain Injury Section, Co-Chair, 2017 - 2021
• Society of Critical Care Medicine, Annual Meeting Improvement Committe, Committee member, 2016 - 2020
• European Society of Intensive Care Medicine, Member, 2008 - Present
• American Academy of Neurology, Member, 2004 - Present

• Early Lumbar drainage to Abort Severe Traumatic IntraCranial hypertension (ELASTIC): A phase 1 randomized, allocation-concealed, open-label, safety, and feasibility clinical trial, Military Traumatic Brain Injury Initiative (MTBI2), Bethesda, PI
• The Brain Trauma Foundation – Military Traumatic Brain Injury Initiative Center for Guidelines, Military Traumatic brain Injury Initiative (MTBI2), Bethesda, Co-I

• Mangat HS, Chiu YL, Gerber LM, Alimi M, Ghajar J, Härtl R. 2015. Hypertonic saline reduces cumulative and daily intracranial pressure burdens after severe traumatic brain injury.. Journal of neurosurgery, 122 (1), 202-10
• Mangat HS, Wu X, Gerber LM, Schwarz JT, Fakhar M, Murthy SB, Stieg PE, Ghajar J, Härtl R. 2020. Hypertonic Saline is Superior to Mannitol for the Combined Effect on Intracranial Pressure and Cerebral Perfusion Pressure Burdens in Patients With Severe Traumatic Brain Injury.. Neurosurgery, 86 (2), 221-230
• Mangat HS, Musah A, Luedtke S, Syed AA, Maramattom BV, Maruthanal J, Bosman A, Kostkova P. 2022. Analyses of reported severe adverse events after immunization with SARS-CoV-2 vaccines in the United States: One year on.. Frontiers in public health, 10, 972464
• Hutchinson PJ, Jalloh I, Helmy A, Carpenter KL, Rostami E, Bellander BM, Boutelle MG, Chen JW, Claassen J, Dahyot-Fizelier C, Enblad P, Gallagher CN, Helbok R, Hillered L, Le Roux PD, Magnoni S, Mangat HS, Menon DK, Nordström CH, O'Phelan KH, Oddo M, Perez Barcena J, Robertson C, Ronne-Engström E, Sahuquillo J, Smith M, Stocchetti N, Belli A, Carpenter TA, Coles JP, Czosnyka M, Dizdar N, Goodman JC, Gupta AK, Nielsen TH, Marklund N, Montcriol A, O'Connell MT, Poca MA, Sarrafzadeh A, Shannon RJ, Skjøth-Rasmussen J, Smielewski P, Stover JF, Timofeev I, Vespa P, Zavala E, Ungerstedt U. 2015. Consensus statement from the 2014 International Microdialysis Forum.. Intensive care medicine, 41 (9), 1517-28
• Johnston KC, Bruno A, Pauls Q, Hall CE, Barrett KM, Barsan W, Fansler A, Van de Bruinhorst K, Janis S, Durkalski-Mauldin VL. 2019. Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.. JAMA, 322 (4), 326-335
• Hanley Daniel F, Thompson Richard E, Rosenblum Michael, Yenokyan Gayane, Lane Karen, McBee Nichol, Mayo Steven W, Bistran-Hall Amanda J, Gandhi Dheeraj, Mould W Andrew, Ullman Natalie, Ali Hasan, Carhuapoma J Ricardo, Kase Carlos S, Lees Kennedy R, Dawson Jesse, Wilson Alastair, Betz Joshua F, Sugar Elizabeth A, Hao Yi, Avadhani Radhika, Caron Jean-Louis, Harrigan Mark R, Carlson Andrew P, Bulters Diederik, LeDoux David, Huang Judy, Cobb Cully, Gupta Gaurav, Kitagawa Ryan, Chicoine Michael R, Patel Hiren, Dodd Robert, Camarata Paul J, Wolfe Stacey, Stadnik Agnieszka, Money P Lynn, Mitchell Patrick, Sarabia Rosario, Harnof Sagi, Barzo Pal, Unterberg Andreas, Teitelbaum Jeanne S, Wang Weimin, Anderson Craig S, Mendelow A David, Gregson Barbara, Janis Scott, Vespa Paul, Ziai Wendy, Zuccarello Mario, Awad Issam A, Abdul-Rahim Azmil, Abou-Hamden Amal, Abraham Michael, Ahmed Azam, Alba Carlos Alarcon, Aldrich E. Francois, Altschul David, Amin-Hanjani Sepideh, Anderson Doug, Ansari Safdar, Antezana David, Ardelt Agnieszka, Arikan Fuat, Baguena Marcelino, Baker Alexandra, Barrer Steven J, Becker Kyra J, Bergman Thomas, Boström Azize, Braun Jamie, Brindley Peter, Broaddus William C, Brown Robert, Buki Andras, Cao Bing, Cao Ying, Carrion-Penagos Julian, Chalela Julio, Chang Tiffany, Chorro Indalecio Moran, Chowdhry Shakeel, Corral Luisa, Csiba Laszlo, Davies Jason, Díaz Alberto Torres, Derdeyn Colin P, Diringer Michael, Dlugash Rachel, Ecker Robert, Economas Tracey, Enriquez Pedro, Ezer Erzsebet, Fan Yuhua, Feng Hua, Franz Douglas, Freeman W. David, Fusco Matthew, Galicich Walter, Gelea Mary Leigh, Goldstein Joshua, Gonzalez Alejandro Carrasco, Grabarits Christina, Greenberg Steven, Gress Daryl, Gu Eugene, Hall Christiana, Hernandez Fernando Muñoz, Hoesch Robert, Hoh Brian L, Houser Jennifer, Hu Rong, Huang Yi, Hussain Mohammed Akbar, Insinga Salvatore, Jadhav Ashutosh, Jaffe Jennifer, Jahromi Babak S, Jallo Jack, James Michael, James Robert F, Jankowitz Brian, Jeon Esther, Jichici Draga, Jonczak Karin, Jonker Ben, Karlen Nicki, Keric Naureen, Kerz Thomas, Knopman Jared, Koenig Carolyn, Krishnamurthy Satish, Kumar Avinash, Kureshi Inam, Laidlaw John, Lakhanpal Arun, Latorre Julius Gene, Leifer Dana, Leiphart James, Lenington Sarah, Li Yunke, Lopez George, Lovick Darren, Lumenta Christianto, Luo Jinbiao, Maas Matthew B, MacDonald Joel, MacKenzie Larami, Madan Vikram, Majkowski Ryan, Major Otto, Malhorta Rishi, Malkoff Marc, Mangat Halinder, Maswadeh Ahmed, Matouk Charles, McArthur Kate, McCaul Scott, Medow Joshua, Mezey Geza, Mighty Janet, Miller David, Mohan Krishna K, Muir Keith, Muñoz Lorenzo, Nakaji Peter, Nee Alex, Nekoovaght-Tak Saman, Nyquist Paul, O'Kane Roddy, Okasha Mohamed, O'Kelly Cian, Ostapkovich Noeleen, Pandey Aditya, Parry-Jones Adrian, Perla Krissia Rivera, Pollack Ania, Polster Sean, Pouratian Nader, Quinn Terry, Rajajee Ventatakrishna, Reddy Kesava, Rehman Mohammed, Reimer Ronald, Rincon Fred, Rybinnik Igor, Sanchez Baltasar, Sansing Lauren, Schneck Michael, Schuerer Ludwig, Schul David, Schweitzer Jeffrey, Seder David B, Seyfried Donald, Sheth Kevin, Spiotta Alejandro, Stechison Michael, Szabo Katalin, Tamayo Gonzalo, Tanczos Krisztian, Taussky Philipp, Terry John, Testai Fernando, Thomas Kathrine, Thompson Carol B, Thompson Gregory, Torner James C, Tran Huy, Tucker Kristi, Ungar Lior, Varelas Panos, Vargas Nataly Montano, Vatter Hartmut, Venkatasubramanian Chitra, Vermillion Krista, Vollmer Dennis, Wang Yan, Wang Ying, Wen Jiajun, Whitworth Louis Tony, Willis Byron, Wrencher Myriha, Wright Shawn E, Xu Yongge, Yanase Lisa, Yi Xuxia, Yu Zhiyuan, Zomorodi Ali. 2019. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. The Lancet, 393 (10175), 1021-1032. https://doi.org/10.1016/s0140-6736(19)30195-3
• Forgacs PB, Allen BB, Wu X, Gerber LM, Boddu S, Fakhar M, Stieg PE, Schiff ND, Mangat HS. 2022. Corticothalamic Connectivity in Aneurysmal Subarachnoid Hemorrhage: Relationship with Disordered Consciousness and Clinical Outcomes.. Neurocritical care, 36 (3), 760-771
• Hawryluk Gregory WJ, Lulla a, Bell Randy, Jagoda Andy, Mangat Halinder S, Bobrow BJ, Ghajar Jamshid. 2023. Guidelines for Prehospital Management of Traumatic Brain Injury 3rd edition. Neurosurgery