Donald A. Neff, M.D.

Professional Background

Donald Neff, MD, FACS, serves as an Associate Professor of Urology at the University of Kansas Medical Center. A Wisconsin native, his journey into healthcare began as a firefighter/paramedic in Janesville, WI. This ignited a deep commitment to patient care, ultimately leading to medical school. He completed medical school and his urology residency at the Medical College of Wisconsin, earning multiple honors for academic excellence and teaching during residency.

Before joining KU, Dr. Neff practiced urology in Janesville and Lake Geneva, Wisconsin. His clinical practice today centers on benign prostatic hyperplasia (BPH), where he holds particular expertise in advanced techniques like prostate enucleation and Aquablation therapy. Recognized as a thought leader in BPH surgical management, he actively refines techniques, develops protocols, and advances physician training in these areas.
Dr. Neff also brings extensive surgical experience to the management of urologic trauma and kidney stones, always prioritizing a patient-centered approach. Teaching activities include urological resident education, and continuing education activities for practicing urologists.

For over ten years, Dr. Neff has demonstrated his commitment to global health through annual medical mission trips to Honduras, providing surgical care and training in underserved communities.

Embracing innovation, Dr. Neff is leaning into the AI revolution, working to integrate artificial intelligence into urologic care. He is developing physician-led tools using large language models aimed at enhancing patient education, optimizing clinical workflows, and supporting personalized, data-driven treatment decisions.

Dr. Neff is a Fellow of the American College of Surgeons and an active member of the American Urological Association.

• BS, Biology, University of Wisconsin - Whitewater, Whitewater, WI
• Internship, Urology, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI
• Residency, Urology, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI

• American Board of Urology
• Kansas Board of Healing Arts
• Missouri Board of Registration for the Healing Arts
• Wisconsin Department of Safety and Professional Services

• American College of Surgeons, Member, 2015 - Present
• Alpha Omega Alpha, Member, 2008 - Present
• American Urological Association, Member, 2008 - Present

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• Willian Ito, Dillon Prokop, Mario Ito, Whiles Bristol, Neff Donald, Duchene David, Molina Wilson. 2023. The Vortex Effect in Minimally Invasive Percutaneous Nephrolithotomy. Urology. https://pubmed.ncbi.nlm.nih.gov/37482100/
• Neff DA, See WA. 2011. Laparoscopic mesh herniorrhaphy: impact on outcomes associated with radical retropubic prostatectomy.. Urologic oncology, 29 (1), 66-9
• Pagel PS, Krolikowski JG, Neff DA, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC. 2006. Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo.. Anesthesia and analgesia, 102 (5), 1348-54
• Woller M, Tessmer S, Neff D, Nguema AA, Roo BV, Waechter-Brulla D. 2001. Leptin stimulates gonadotropin releasing hormone release from cultured intact hemihypothalami and enzymatically dispersed neurons.. Experimental biology and medicine (Maywood, N.J.), 226 (6), 591-6
• Ito Willian, Igel Daniel, Whiles Bristol, Sardieu Mahaela, Neff Donald, Duchene David, Molina Wilson. 2023. Breakage Costs in Flexible Ureteroscopy: Digital vs. Fiberoptic Modalities. Urology. https://pubmed.ncbi.nlm.nih.gov/36400269/
• Miller Caleb S, Whiles Bristol B, Ito Willian E, Machen Edward, Thompson Jeffrey A, Duchene David A, Neff Donald A, Molina Wilson R. 2023. Image Distortion During Flexible Ureteroscopy: A Laboratory Model Comparing Super Pulsed Thulium Fiber Laser vs High-Power Ho:YAG Laser. Journal of Endourology, 37 (1), 99-104
• Donald Neff, Kellerman Rick. 2024. Urinary Tract Infections in the Male
• Vergamini Lucas B, Ito Willian, Choi B Nicholas, Du Holly E, Sardiu Mihaela E, Neff Donald, Duchene David A, Molina Wilson R, Whiles Bristol B. 2024. Holmium:yttrium‐aluminium‐garnet laser with MOSES technology is more efficient than thulium fibre laser in supine mini‐percutaneous nephrolithotomy. BJU International, 134 (2), 276-282. https://doi.org/10.1111/bju.16392
• Ito Willian, Prokop Dillon, Whiles Bristol, Sardiu Mahaela, Smith Holly, Neff Donald, Duchene David, Molina Wilson. 2024. Impact of Renal Access Angle and Speed of Nephroscope Retrieval Movements on the Vortex Effect. Urology. https://pubmed.ncbi.nlm.nih.gov/37951359/
• Vergamini Lucas B, Molina Wilson R, Ito Willian, Tverye Aaron, Walcott Quinnlyn, Du Holly E, Sardiu Mihaela E, Valadon Crystal, Hanna Daniel R, Neff Donald, Duchene David A, Whiles Bristol B. 2024. Intrarenal pressure and flow rate profile using LithoVue™ elite: impact of different irrigation systems and working channel instruments. World Journal of Urology, 42 (1). https://doi.org/10.1007/s00345-024-05125-8