Charles B. Porter, MD

Professional Background

Dr. Charles Porter has been actively involved in heart failure and cardiac transplantation for over thirty years in Kansas City. He worked with Dr. William Reed to help launch the third heart transplant program in Missouri and the first in Kansas City in 1985. Dr. Porter subsequently received recognition as one of the first Medicare designated heart transplant cardiologists in Kansas City. Dr. Porter became one of the founding members of the Working Group of Transplant Cardiologists that developed the Transplant Cardiology Database, housed at the University of Alabama Birmingham, that provided clinical data supporting the publication of countless studies on the outcomes of cardiac transplant patients. He established membership in the International Society for Heart Transplantation in 1986 before it had expanded to its current form as the International Society for Heart and Lung Transplantation. He was a co-author of the research paper that introduced and validated the Kansas City Cardiomyopathy Questionnaire that has subsequently become one of the leading patient-centered quality of life surveys in the world. His continuous care for cardiac transplant patients in Kansas City since 1985 has allowed him to guide many heart transplant patients to decades of survival as his patients now approaching 30 years of survival after transplant.


Nearly a decade ago he began collaborative work with the cancer specialists at KU Hospital that helped allow cancer patients who were developing heart failure due to their cancer treatment to continue their cancer treatments rather than be forced to stop or interrupt their vital cancer chemotherapies. Since then this field has expanded rapidly and is widely recognized as a specialty area known as Cardio-oncology. Dr. Porter is the founding Medical Director of cardio-oncology at the University of Kansas Medical Center.

• BS, Bachelor of Science, Southern Methodist Univ.
• MD, Doctor of Medicine, Univ. of Kansas-Medical Ctr.
• Internship, Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas
• Residency, Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas
• Other, Cardiovascular Diseases, University of Texas Health Services Center, San Antonio, Texas

• America Heart Association, America Heart Association, Member, 2019 - Present
• ACC, ACC Cardio-Oncology Patient Education Work Group, Member, 2016 - Present
• America Heart Association, America Heart Association, President, 1989 - 1991
• America Heart Association, America Heart Association, Member, 1986 - Present
• American College of Cardiology-Member, American College of Cardiology, Member, 1980 - Present

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Research

Overview

Dr. Porter was an investigator in clinical research that helped establish the role medications that have now become the mainstay components of therapy for heart failure, the beta blockers and the blockers of the angiotensin system that cause progression of heart failure. He was the principle investigator at the University of Kansas Hospital (TUKH) in the landmark COMPANION Trial of biventricular pacing defibrillators that helped establish these devices as another mainstay for recovery of cardiac function and prevention of sudden cardiac death in patients with heart failure and damaged cardiac electrical conduction.

• COAPT, Abbott Vascular, Co-I
• CHAMP HF, Novartis, Co-I
• INVESTED, NIH, Co-I
• GALACTIC HF, Amgen, Co-I
• PIONEER HF, Novartis, Co-I

• Lenihan Daniel, Carver Joseph, Porter Charles B., Liu Jennifer E, Dent Susan, Thavendiranathan Paaladinesh, Mitchell Joshua D., Nohria Anju, Fradley Michael G, Pusic Iskra, Stockerl-Goldstein Keith, Blaes Anne, Lyon Alexander R, Ganatara Sarju, Lopez-Fernandez Teresa, O'Quinn Rupal, Minotti Giorgio, Szmit Sebastian, Cardinale Daniela, Alvarez-Cardona Jose, Curigliano Giuseppe, Neilan Tomas G, Herrmann Joerg. 2020. Cardio-Oncology Care in the Era of the COVID-19 Pandemic: An International Cardio-Oncology Society(ISCOS) Statement. CA: A Cancer Journal for Clinicians, 1-25. https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21635
• Curigliano G, Leniham D, Fradley M, Ganatra S, Barac A, Blaes A, Herrmann J, Porter C, Lyon AR, Lancellotti P, Patel A, DeCara J, Mitchell J, Harrison E, Moselehi J, Witteles R, Calabro MG, Orecchia R, Azamubja E de, Zamorano JL, Krone R, Iakobishvili Z, Carver J, Armenian S, Ky B, Cardinale D, Cipolla CM, Dent S, Jordan K. 2020. Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consenss recommendations. Annals of Oncology, 31 (2). https://www.sciencedirect.com/science/article/pii/S0923753419360806?via%3Dihub
• Okwuosa Tochi, Morgans Alicia, Rhee June-Wha, Reding Kerryn W, Maliski Sally, Plana Juan-Carlos, Volgman Annabelle Santos, Moseley Kendall F, Porter Charles B, Ismail-Khan Roohi. 2020. Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications. Circulation: Genomic and Precision Medicine
• Shah Zubair, Porter Charles. 2018. Heart Failure: What a non-heart failure specialist needs to know?, 125-156
• Lenihan Daniel J, Hartlage Gregory, Decara Jeannie, Blaes Annie, Finet Emanuel, Lyon Alexander R, Cornell Robert F, Moslehi Javid, Oliveira Guilherme H, Murtagh Gillian, Fisch Michael, Zeevi Gary, Jakobishviu Azaz, Witteles Ron, Patel Aaarti `, Harrison Eric, Fradley Michael, Curigliano Giuseppe, Lenneman Carrie Geisberg, Magalhaes Andreia, Krone Ron, Porter Charles, Parasher Susmita, Dent Susan, Douglas Pamela, Carver Joseph. 2016. Cardio-Oncology Training: A Proposal From the International Cardioncology Society and Canadian Cardiac Oncology Network for a New Multidisciplinary Specialty. J Cardiac Fail , 22:465–471. https://www.sciencedirect.com/science/article/pii/S1071916416300057?via%3Dihub
• Burnett D, Kluding P, Porter CB, Fabian C, Klemp J. 2013. Cardiorespiratory fitness in breast cancer survivors. SpringerPlus, 2:68
• Porter CB, Slosky D. 2011. Interventional strategies to manage heart failure in patients with cancer, Jul;7(3): 395-402
• Whellan David J, Ousdigian Kevin T, Al-Khatib Sana M, Pu Wenji, Sarkar Shantanu, Porter Charles B, Pavri Behzad B, O'Connor Christopher M. 2010. Combined Heart Failure Device Diagnostics Identify Patients at Higher Risk of Subsequent Heart Failure Hospitalizations. Journal of the American College of Cardiology, 55 (17), 1803-1810. https://doi.org/10.1016/j.jacc.2009.11.089
• Parks Sharie B, Kushner Jessica D, Nauman Deirdre, Burgess Donna, Ludwigsen Susan, Peterson Amanda, Li Duanxiang, Jakobs Petra, Litt Michael, Porter Charles B, Rahko Peter S, Hershberger Ray E. 2008. Lamin A/C mutation analysis in a cohort of 324 unrelated patients with idiopathic or familial dilated cardiomyopathy. American Heart Journal, 156 (1), 161-169. https://doi.org/10.1016/j.ahj.2008.01.026