Lexie Brown, Ph.D.

Professional Background

I have worked collaboratively with KUMC research teams in project development, database design, data monitoring, data management, and statistical analyses for a variety of multisite randomized controlled trials. I successfully helped implement large, multisite trials, many funded by PCORI (Patient Centered Outcomes Research Institute), and applied a variety of statistical methods including Bayesian adaptive designs for comparative effectiveness research (PAIN-CONTRoLS, CER-1306-02496), a phase III trial (ADORE, 1R01HD083292), as well as a cluster randomized trial for weight loss (REPOWER, OB-1402-09413). Along with colleagues in the KUMC Department of Biostatistics & Data Science, I have formed trusted relationships with many PIs and research teams. Some of my time has also included expanding my research to statistics education, where I developed and instruct statistics-related courses to graduate students. This teaching experience has augmented my ability to discuss and communicate key statistical and methodological concepts to those whose background is not in statistics or data management. I work with and provide statistical expertise for many graduate student research projects. .

• BS, Statistics, University of Missouri-Kansas City, Kansas City, Missouri
• MS, Biostatistics, University of Kansas Medical Center, Kansas City, Kansas
• PhD, Biostatistics, University of Kansas Medical Center, Kansas City, Kansas

• SAS

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• Brown Alexandra R, Gajewski Byron J, Mudaranthakam Dinesh, Pasnoor Mamatha, Dimachkie Mazen, Jawdat Omar, Herbelin Laura, Mayo Matthew S, Barohn Richard J. 2023. Conducting a Bayesian Multi-Armed Trial with Response Adaptive Randomization for Comparative Effectiveness of Medications for CSPN. Contemp Clin Trials Commun, 36, 101220. https://www.ncbi.nlm.nih.gov/pubmed/37965484/
• Brown AR, Gajewski BJ, Aaronson LS, Mudaranthakam DP, Hunt SL, Berry SM, Quintana M, Pasnoor M, Dimachkie MM, Jawdat O, Herbelin L, Barohn RJ. 2016. A Bayesian comparative effectiveness trial in action: developing a platform for multisite study adaptive randomization.. Trials, 17 (1), 428. https://www.ncbi.nlm.nih.gov/pubmed/27577191/
• Leavens ELS, Mayo MS, Brown AR, Cox LS, Ellerbeck EF, Ahluwalia JS, Nollen NL. 2023. Early Treatment Response in Black Smokers Undergoing Pharmacotherapy for Smoking Cessation: A Secondary Analysis of a Randomized Clinical Trial.. JAMA Netw Open, 6 (9), e2334695. https://www.ncbi.nlm.nih.gov/pubmed/37728930/
• Lambart Leah, Nollen Nicole L, Mayo Matthew S, Funk Olivia, Leavens Eleanor, Cruvinel Erica, Brown Alexandra, Ahluwalia Jasjit S, Sanderson Cox Lisa. 2024. The impact of blunt use on smoking abstinence among Black adults: Secondary analysis from randomized controlled smoking cessation clinical trial. Addictive Behaviors, 148, 107877. https://doi.org/10.1016/j.addbeh.2023.107877
• Gajewski BJ, Carlson SE, Brown AR, Mudaranthakam DP, Kerling EH, Valentine CJ. 2022. The value of a two-armed Bayesian response adaptive randomization trial.. J Biopharm Stat, 33 (1), 43-52. https://www.ncbi.nlm.nih.gov/pubmed/36411742/
• Desouza Cyrus V, Johnson‐Rabbett Brianna E, Gajewski Byron, Brown Alexandra, Ellerbeck Edward F, VanWormer Jeffrey J, Befort Christie. 2022. The effect of nonpharmaceutical weight‐loss interventions in rural patients with diabetes: RE‐POWER Diabetes. Obesity, 30 (4), 884-892. https://doi.org/10.1002/oby.23392
• Gustafson KM, Christifano DN, Hoyer D, Schmidt A, Carlson SE, Colombo J, Mathis NB, Sands SA, Chollet-Hinton L, Brown AR, Mudaranthakam DP, Gajewski BJ. 2021. Prenatal docosahexaenoic acid effect on maternal-infant DHA-equilibrium and fetal neurodevelopment: a randomized clinical trial.. Pediatr Res, 14 (16). https://www.ncbi.nlm.nih.gov/pubmed/34552200/
• Rubenstein D, Aston ER, Nollen NL, Mayo MS, Brown AR, Ahluwalia JS. 2020. Factors Associated With Cannabis Use Among African American Nondaily Smokers.. J Addict Med, 14 (5), e170-e174. https://www.ncbi.nlm.nih.gov/pubmed/32187115/
• Carlson SE, Gajewski BJ, Valentine CJ, Sands SA, Brown AR, Kerling EH, Crawford SA, Buhimschi CS, Weiner CP, Cackovic M, DeFranco EA, Mudaranthakam DP, Rogers LK. 2023. Early and late preterm birth rates in participants adherent to randomly assigned high dose docosahexaenoic acid (DHA) supplementation in pregnancy . Clin Nutr, 42 (2), 235-243. https://www.ncbi.nlm.nih.gov/pubmed/36680919/
• Carlson SE, Gajewski BJ, Valentine CJ, Kerling EH, Weiner CP, Cackovic M, Buhimschi CS, Rogers LK, Sands SA, Brown AR, Mudaranthakam DP, Crawford SA, DeFranco EA. 2021. Higher dose docosahexaenoic acid supplementation during pregnancy and early preterm birth: A randomised, double-blind, adaptive-design superiority trial.. EClinicalMedicine, 36, 100905