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References

Schonfeld M, Nataraj K, Mah S, Zhong W, Weinman SA, Tikhanovich I. Acute Phase Response-driven Hepatic Niche Remodeling Promotes Fibrosis Resolution After Alcohol Cessation. Cell Mol Gastroenterol Hepatol. 2026;20(3):101689. doi: 10.1016/j.jcmgh.2025.101689. Epub 2025 Nov 29. PMID: 41320154

Yuquimpo K, Averilla J, Li Z, Ghosh P, Rooge S, Pulido Ruiz IA, Dunn W, Gunewardena S, Wozniak AL, Tikhanovich I, Weinman SA. Liver Macrophage Changes during Early Adaptation to Alcohol Exposure. Am J Pathol. 2026 Jan;196(1):272-287. doi: 10.1016/j.ajpath.2025.10.004. Epub 2025 Oct 31. PMID: 41177326

Nataraj K, Schonfeld M, Mah S, Li Z, Weinman S, Tikhanovich I. Alcohol-induced KDM5B activation in hepatocytes drives pathogenic cell-cell communication, leading to loss of liver function. Hepatol Commun. 2025 Aug 15;9(9):e0771. doi: 10.1097/HC9.0000000000000771. eCollection 2025 Sep 1. PMID: 40824250

Schonfeld M, Nataraj K, Mah S, Weinman S, Tikhanovich I. Continuous Activation of C/EBPβ Transcription Factor Prevents Fibrosis Resolution After Alcohol Cessation. Cell Mol Gastroenterol Hepatol. 2025;19(9):101525. doi: 10.1016/j.jcmgh.2025.101525. Epub 2025 Apr 26. PMID: 40288442

Schonfeld M, Nataraj K, Weinman S, Tikhanovich I. C/EBPβ transcription factor promotes alcohol-induced liver fibrosis in males via HDL remodeling. Hepatol Commun. 2025 Feb 19;9(3):e0645. doi: 10.1097/HC9.0000000000000645. eCollection 2025 Mar 1. PMID: 39969482

Osna NA, Tikhanovich I, Ortega-Ribera M, Mueller S, Zheng C, Mueller J, Li S, Sakane S, Weber RCG, Kim HY, Lee W, Ganguly S, Kimura Y, Liu X, Dhar D, Diggle K, Brenner DA, Kisseleva T, Attal N, McKillop IH, Chokshi S, Mahato R, Rasineni K, Szabo G, Kharbanda KK. Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression Biomolecules. 2024 Mar 27;14(4):404. doi: 10.3390/biom14040404. PMID: 38672422

Sasaki K, Rooge S, Gunewardena S, Hintz JA, Ghosh P, Pulido Ruiz IA, Yuquimpo K, Schonfeld M, Meta H, Stevenson HL, Saldarriaga OA, Arroyave E, Tikhanovich I, Wozniak AL, Weinman SA. Kupffer cell diversity maintains liver function in alcohol-associated liver disease. Hepatology. 2024 Apr 30. doi: 10.1097/HEP.0000000000000918. Online ahead of print. PMID: 38687563

Nataraj K, Schonfeld M, Rodriguez A, Tikhanovich I. Protective role of 17β-estradiol in alcohol-associated liver fibrosis is mediated by suppression of integrin signaling Hepatol Commun. 2024 May 3;8(5):e0428. doi: 10.1097/HC9.0000000000000428. eCollection 2024 May 1. PMID: 38704651

Nataraj K, Schonfeld M, Rodriguez A, Sharma M, Weinman S, Tikhanovich I. Androgen Effects on Alcohol-induced Liver Fibrosis Are Controlled by a Notch-dependent Epigenetic Switch. Cell Mol Gastroenterol Hepatol. 2025;19(1):101414. doi: 10.1016/j.jcmgh.2024.101414. Epub 2024 Sep 28. PMID: 39349250

Elias, G., Schonfeld, M., Saleh, S., Parrish, M., Barmanova, M., Weinman, S. A, Tikhanovich, I. (2023). Sepsis induced endothelial dysfunction drives acute-on-chronic liver failure via Angiopoietin-2-HGF-C/EBPβ pathway. Hepatology (Baltimore, Md.). 36943063

Schonfeld, M., O'Neil, M., Weinman, S. A, Tikhanovich, I. (2023). Alcohol-induced epigenetic changes prevent fibrosis resolution after alcohol cessation in miceresolution. Hepatology (Baltimore, Md.). 37943941

KU School of Medicine

University of Kansas Medical Center
Department of Internal Medicine
Division of Gastroenterology, Hepatology and Motility
Mailstop 1023
3901 Rainbow Boulevard
Kansas City, KS 66160
Phone: 913-588-6019
Fax: 913-588-3975