Other Topics
Clinical Studies - Other Topics
| Study Title and PI | Funding Source | ClinicalTrials.gov Number (if applicable) | Brief Summary |
|---|---|---|---|
| Mitigating the pro-inflammatory phenotype of obesity (MAPLE) PI: Seth Holwerda |
Investigator Initiated | NCT04934228 | The purpose of this study is to examine the hypothesis that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell expression of inflammatory markers (e.g., TNF-α, IL-6). Our study is a prospective study using a randomized, double-blinded design to test 4 weeks of SNA blockade (oral clonidine) compared with a BP-lowering control condition (diuretic, hydrochlorothiazide) or a placebo. |
| Monitered Anesthesia Care in In Burn Dressing Changes PI: Anthony Kovac |
Investigator Initiated | Monitored anesthesia care (MAC) is one method of providing sedation and analgesia for burn dressing changes. A previous retrospective study described the efficacy and safety of MAC in burn patients. The primary aim of this study is to further that research with a prospective, observational study of patient, burn nurse or technician, and anesthesia provider satisfaction with MAC for burn dressing change. |
Recent Publications
Extraocular Manifestations of Obstructive Sleep Apnea as a Potential Screening Tool for Perioperative Complications: A Case Control Study.
Folsom M, Diaz J, Lowe N, Dronavalli A, Sokol JA, Ajlan RS, George A, Ji Y, Nazir N. Obes Surg. 2025;35(12):5062-5068.
TLR4 deletion reduces small fiber sensory abnormalities and nerve degeneration in diabetic male mice.
Crowards S, Ryals J, Heslop L, Hauser W, Totta-Griese G, Madden T, Wright DE. Neuroscience. 2025;589:268-279.
Defining and Managing End-of-Life Respiratory Changes in Adult Home Hospice Patients: A Systematic Review.
Donehower AK, Doering M, White Makinde K, Bharadwaj A, Daniels JD, Gebreegziabher Y, McPherson ML, White P, Mayahara M, Oliver DP. J Palliat Med. 2025. Online ahead of print.
Biplane Imaging using Portable Ultrasound Devices for Cardiac Imaging.
Beshara M, Bittner EA, Chang MG. Ann Card Anaesth. 2025;28(4):490-495.
Plastics Makes Perfect: A Collaborative, Cost-effective Approach to Multilevel Cadaveric Learning.
Godbe K, Bird C, Vance D, Nazir N, Kilgore L, Berbel G, Megee D, Garg R, Butterworth J, Farmer R. Plast Reconstr Surg Glob Open. 2025;13(9):e7081