Past Interstitial Lung Disease (ILD) and Sarcoidosis Trials
| Years | NCT Number |
Study Title |
Principle Investigator |
Sponsor |
|---|---|---|---|---|
| 2012 -2014 | NCT01366209 |
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Efficacy and Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis |
Mark Hamblin |
Intermune, Inc. |
| 2013 - 2015 | NCT00662038 |
An Open-Label Extension Study of the Long-Term Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (IPF) |
Mark Hamblin |
Intermune, Inc. |
| 2013 - 2018 | NCT01890265 |
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of FG-3019 in Patients with Idiopathic Pulmonary Fibrosis |
Mark Hamblin |
Fibrogen, Inc. |
| 2013 - 2018 | NCT01872689 |
A Phase II, Randomized, Double-Blind, Placebo-Controlled, Study to Assess the Efficacy and Safety of Lebrikizumab in Patients with Idiopathic Pulmonary Fibrosis |
Mark Hamblin |
Genentech-Roche, Inc. |
| 2014 - 2017 | NCT01371305 |
Randomized, Double-Blind, Placebo-Controlled,Multiple Dose, Dose-Escalation Study of STX-100 in Patients with Idiopathic Pulmonary Fibrosis (IPF) |
Mark Hamblin |
Biogen MA Inc. |
| 2014 - 2015 | NCT02141087 |
A Treatment Protocol to Allow Patients in the US with Idiopathic Pulmonary Fibrosis Access to Pirfenidone |
Mark Hamblin |
Intermune, Inc. |
| 2016 - 2019 | NCT02550873 |
A Phase 2 Trial to Evaluate the Efficacy of PRM-151 in Subjects with Idiopathic Pulmonary Fibrosis (IPF) |
Mark Hamblin |
Promedior, Inc. |
| 2016 - 2019 | NCT02597933 |
A double blind, randomised, placebo-controlled trial evaluating efficacy and safety of oral nintedanib treatment for at least 52 weeks in patients with Systemic Sclerosis associated Interstitial Lung Disease(SSc-ILD). |
Mark Hamblin |
Boehringer Ingelheim |
| 2016 - 2018 | NCT02846324 |
A Phase II randomized, double-blind, placebo-controlled study of GBT440 to evaluate the safety, tolerability, pharmacokinetics and effect on hypoxemia in subjects with Idiopathic Pulmonary Fibrosis (IPF) |
Mark Hamblin |
Global Blood Therapeutics |
| 2016 - 2023 | NCT02758808 |
PFF Patient Registry Protocol |
Mark Hamblin |
University of Michigan |
| 2017 - 2018 | NCT02802345 |
A 24-week, double-blind, randomized, parallel-group study evaluating the efficacy and safety of oral nintedanib coadministered with oral sildenafil, compared to treatment with nintedanib alone, in patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment |
Lucas Pitts |
Boehringer Ingelheim |
| 2017 - 2019 | NCT02999178 |
A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD) |
Lucas Pitts |
Boehringer Ingelheim |
| 2018 - 2021 | NCT03313180 |
An open-label extension trial to assess the long term safety of nintedanib in patients with ‘Systemic Sclerosis associated Interstitial Lung Disease’ (SSc-ILD) SENSCIS-ON |
Mark Hamblin |
Boehringer Ingelheim |
| 2018 - 2020 | NCT03573505 |
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of BG00011 in Patients With Idiopathic Pulmonary Fibrosis |
Mark Hamblin |
Biogen MA Inc. |
| 2018 - 2021 | NCT02759120 |
Study of Clinical Efficacy of Antimicrobial Therapy Strategy Using Pragmatic Design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) |
Mark Hamblin |
NIH/NHLBI |
| 2018 - 2022 | NCT03320070 |
A Phase 5 Multicenter, Randomized, Double Blind, Placebo-Controlled Pilot Study to Assess the Efficacy and Safety of H.P. Acthar Gel in Subjects with Pulmonary Sarcoidosis |
Mark Hamblin |
Mallinckrodt Pharmaceuticals |
| 2019 - 2021 | NCT03711162 |
A Phase 3, randomized, double-blind, parallel-group, placebo-controlled multi-center study to evaluate the efficacy and safety of two doses of GLPG1690 in addition to local standard of care for minimum 52 weeks in subjects with idiopathic pulmonary fibrosis |
Mark Hamblin |
Galapagos |
| 2019 - 2021 | NCT03820726 |
An open-label extension trial of the long-term safety of nintedanib in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD) |
Lucas Pitts |
Fibrogen, Inc. |
| 2020 - 2022 | NCT04419506 |
A Randomised, Double-blind, Placebo-controlled Parallel Group Study in IPF Patients Over 12 Weeks Evaluating Efficacy, Safety and Tolerability of BI 1015550 Taken Orally |
Mark Hamblin |
Boehringer Ingelheim |